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High doses of B12 may worsen the disease and cause irreversible damage to the optic nerve
As the first treatment strategy, conventional synthetic (cs) DMARDs like methotrexate, hydroxychloroquine, sulfasalazine, leflunomide, chloroquine, and gold salts should be used as soon as RA is diagnosed
[2] [4] In experimental models it has been reported to modulate several growth factors and to protect the gastrointestinal mucosa
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